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The majortransporter involved is URAT-1, a member of theOATP family. The expectant treatment of “asymptomatic” supratentorial epidural hematomas.Neurosurgery. Examination may dem-onstrate an ipsilateral anterior cervical bruit and pos-sibly ophthalmoscopic evidence of retinal emboli, suchas one or more Hollenhorst plaques (bright copper oryellowish glinting of reflective cholesterol emboli, oftenlodged at bifurcations of retinal arterioles), or migratingwhite plaques or fixed white plugs associated with plate-let-fibrin and calcific emboli (Fisher, 1959; Hollenhorst,1961; David et al., 1963; Marshall and Meadows, 1968;Hooshmand et al., 1974; Ellenberger and Epstein, 1986).Such microemboli are most commonly associated withatheromatous lesions of the ipsilateral carotid artery, butthey can originate from the aortic arch or carotid siphonor, less commonly, from calcific cardiac valvular dis-ease

Examination may dem-onstrate an ipsilateral anterior cervical bruit and pos-sibly ophthalmoscopic evidence of retinal emboli, suchas one or more Hollenhorst plaques (bright copper oryellowish glinting of reflective cholesterol emboli, oftenlodged at bifurcations of retinal arterioles), or migratingwhite plaques or fixed white plugs associated with plate-let-fibrin and calcific emboli (Fisher, 1959; Hollenhorst,1961; David et al., 1963; Marshall and Meadows, 1968;Hooshmand et al., 1974; Ellenberger and Epstein, 1986).Such microemboli are most commonly associated withatheromatous lesions of the ipsilateral carotid artery, butthey can originate from the aortic arch or carotid siphonor, less commonly, from calcific cardiac valvular dis-ease. At this laterstage of development, the first pharyngeal groove grows toward the developing tubotympanic recess.

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